Supplemental Information Conserved and Divergent Roles of FGF Signaling in Mouse Epiblast Stem Cells and Human Embryonic Stem Cells
نویسندگان
چکیده
Cell Stem Cell, Volume 6 Supplemental Information Conserved and Divergent Roles of FGF Signaling in Mouse Epiblast Stem Cells and Human Embryonic Stem Cells Boris Greber, Guangming Wu, Christof Bernemann, Jin Young Joo, Dong Wook Han, Kinarm Ko, Natalia Tapia, Davood Sabour, Jared Sterneckert, Paul Tesar, and Hans R. Schöler Inventory of Supplemental Information Supplemental Tables are all MS Excel spreadsheets and not part of this supplemental document
منابع مشابه
Conserved and divergent roles of FGF signaling in mouse epiblast stem cells and human embryonic stem cells.
Mouse epiblast stem cells (EpiSCs) are cultured with FGF2 and Activin A, like human embryonic stem cells (hESCs), but the action of the associated pathways in EpiSCs has not been well characterized. Here, we show that activation of the Activin pathway promotes self-renewal of EpiSCs via direct activation of Nanog, whereas inhibition of this pathway induces neuroectodermal differentiation, like ...
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